Side Effects of Lidocaine Mukilteo WA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Therapeutic Health Services/Snohomish
(425) 347-5121x304
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Lakeside Milam Recovery Centers Inc
(425) 670-3664
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Edmonds, WA
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CRC Lynnwood Clinic
(425) 672-7293
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Center for Counseling/Health Resources
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Everett, WA
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Providence Behavioral Health Services
(425) 258-7390
916 Pacific Avenue
Everett, WA
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Coles Counseling Center Inc
(425) 778-7118
8923 236th Street SW
Edmonds, WA
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Alternative Counseling Edmonds
(425) 776-6414
22727 Highway 99
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A New Spirit Recovery Program Inc
(425) 771-1194
22617 76th Avenue West
Edmonds, WA
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Sea Mar Community Health Center
(425) 609-5505
1031 SE Everett Mall Way
Everett, WA
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Substance abuse
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Adolescents, Persons with co-occurring mental and substance abuse disorders, DUI/DWI offenders, Criminal justice clients
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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