Side Effects of Lidocaine Mountlake Terrace WA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Assessment and Treatment Associates
(425) 289-1600
21907 64th Avenue West
Mountlake Terrace, WA
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La Esperanza Health Counseling Servs
(206) 306-2690
19909 64th Avenue West
Lynnwood, WA
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Asian-American Chemical Dependency
(425) 776-1290
5108-196th Street SW
Lynnwood, WA
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Seattle Mental Health
(206) 302-2200x2388
9706 4th Avenue NE
Seattle, WA
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Coles Counseling Center Inc
(425) 778-7118
8923 236th Street SW
Edmonds, WA
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Alderwood Recovery
(425) 478-1000
6405 218th Street SW
Mountlake Terrace, WA
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Outpatient

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Alpine Recovery Services Inc
(425) 778-1136
3924 204th Street SW
Lynnwood, WA
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(800) 562-1240
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TLC Recovery
(206) 363-1992
19940 Ballinger Way NE
Shoreline, WA
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Center for Human Services
(206) 362-7282x8826
17018 15th Avenue NE
Shoreline, WA
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Women, Men
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Recovery Options Northwest
(206) 361-4707x3
2150 North 107th Street
Seattle, WA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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