Side Effects of Lidocaine Mebane NC

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Life Changes Counseling
(336) 228-7600
204 East Elm Street
Graham, NC
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ADS Alcohol and Drug Services
(336) 532-0500
2140 North Church Street
Burlington, NC
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Alamance Regional Medical Center Inc
(336) 538-7888
1240 Huffman Mill Road
Burlington, NC
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(336) 538-7887
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Substance abuse , Detoxification
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Hospital inpatient, Outpatient
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Persons with co-occurring mental and substance abuse disorders
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Annas Resources Inc
(919) 942-8422
976 Martin Luther King Jr Boulevard
Chapel Hill, NC
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Substance abuse
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UNC Department of Psychiatry
(919) 966-6039
1101 Weaver Dairy Road
Chapel Hill, NC
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Substance abuse , Buprenorphine Services
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DUI/DWI offenders, Criminal justice clients
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Residential Treatment Services of
(336) 227-7417
Hall Avenue Facility
Burlington, NC
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Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Women, Men
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Carolina Behavioral Care
(919) 644-0049
105 West Corbin Street
Hillsborough, NC
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Freedom House Recovery Center
(919) 942-2803x18
104 New Stateside Drive
Chapel Hill, NC
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Substance abuse
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Elizabeth Anton
(919) 942-9842
1829 East Franklin Street
Chapel Hill, NC
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders

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Sunrise Casaworks Residence
(919) 960-3775
209-17 Connor Drive
Chapel Hill, NC
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Substance abuse
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Residential long-term treatment (more than 30 days)
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Women, Residential beds for clients' children

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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