Side Effects of Lidocaine Hillsborough NC

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Carolina Behavioral Care
(919) 644-0049
105 West Corbin Street
Hillsborough, NC
Services Provided
Substance abuse , Detoxification
Types of Care
Outpatient

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Freedom House Recovery Center
(919) 425-5474
601 Carlton Avenue
Durham, NC
Services Provided
Substance abuse , Halfway house
Types of Care
Residential short-term treatment (30 days or less)

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Substance Abuse Outpatient Program
(919) 286-0411x7483
1830 Hillandale Road
Durham, NC
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Substance abuse , Buprenorphine Services
Types of Care
Outpatient
Special Programs/Groups
Persons with co-occurring mental and substance abuse disorders

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Holly Fitzgerald LCSW
(919) 942-4778
213 Oxford Hills Drive
Chapel Hill, NC
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Substance abuse
Types of Care
Outpatient

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Sunrise Casaworks Residence
(919) 960-3775
209-17 Connor Drive
Chapel Hill, NC
Services Provided
Substance abuse
Types of Care
Residential long-term treatment (more than 30 days)
Special Programs/Groups
Women, Residential beds for clients' children

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Duke University Medical Center
(919) 684-3850
2213 Elba Street
Durham, NC
Services Provided
Substance abuse , Buprenorphine Services
Types of Care
Outpatient
Special Programs/Groups
Adolescents, Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Pregnant/postpartum women, Women, Men

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Durham Treatment Center
(919) 286-1509
2526 Erwin Road
Durham, NC
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
Types of Care
Outpatient

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Ctr for Adol Sub Use Trtmt (CAST)
(919) 668-5559
402 Trent Drive
Durham, NC
Services Provided
Substance abuse
Types of Care
Outpatient
Special Programs/Groups
Adolescents, Persons with co-occurring mental and substance abuse disorders

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UNC Department of Psychiatry
(919) 966-6039
1101 Weaver Dairy Road
Chapel Hill, NC
Services Provided
Substance abuse , Buprenorphine Services
Types of Care
Outpatient
Special Programs/Groups
DUI/DWI offenders, Criminal justice clients
Language Services
ASL or other assistance for hearing impaired

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Annas Resources Inc
(919) 942-8422
976 Martin Luther King Jr Boulevard
Chapel Hill, NC
Services Provided
Substance abuse
Types of Care
Outpatient

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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