Side Effects of Lidocaine Lexington Park MD

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Substance Abuse Rehabilitation Program
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Patuxent River, MD
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Calvert Substance Abuse Services
(410) 535-3079
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Lusby, MD
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(301) 997-1300
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Leonardtown, MD
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Mechanicsville, MD
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Compass Halfway House
(301) 862-4212
44863 Saint Andrews Church Road
California, MD
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(301) 863-6661
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
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Persons with co-occurring mental and substance abuse disorders, Pregnant/postpartum women, Women, Criminal justice clients

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Counseling Services of
(301) 373-4215
24930 Old Three Notch Road
Hollywood, MD
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Marcey Halfway House
(301) 475-4701
41550 Doctors Crossing Road
Leonardtown, MD
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Persons with co-occurring mental and substance abuse disorders, Women

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Calvert Substance Abuse Services
(410) 535-3079x13
315 Stafford Road
Prince Frederick, MD
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Substance abuse
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Outpatient
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Criminal justice clients

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Calvert Treatment Facility
(410) 535-8930
125 Fairground Road
Prince Frederick, MD
Hotline
(410) 535-8930
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Substance abuse , Halfway house, Buprenorphine Services
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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