Side Effects of Lidocaine Clinton MD

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Malcolm Grow Medical Center Addiction
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Second Genesis Inc
(301) 568-4822
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Upper Marlboro, MD
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Institute of Life and Health Alcohol
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5311 Water Street
Upper Marlboro, MD
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Outpatient
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Concerned Citizens on
(202) 563-3209
3115 Martin Luther King Avenue SE
Washington, DC
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Substance abuse
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Pregnant/postpartum women, Women, DUI/DWI offenders

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Family and Medical Counseling Service
(202) 889-7900
2041 Martin Luther King Avenue SE
Washington, DC
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Substance abuse
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Persons with HIV/AIDS, DUI/DWI offenders, Criminal justice clients
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Alcohol and Drug Recovery (ADR)
(301) 735-6071
7610 Pennsylvania Avenue
Forestville, MD
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Substance abuse
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Outpatient
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DUI/DWI offenders

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Another Spring Counseling Services
(301) 574-4200
14526 Church Street
Upper Marlboro, MD
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Substance abuse
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Stepping Stone Treatment Program Inc
(301) 574-1103
14749 Main Street
Upper Marlboro, MD
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Substance abuse
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Outpatient
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DUI/DWI offenders

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Federal City Recovery Services
(202) 562-4939
920 Bellevue Street SE
Washington, DC
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Substance abuse
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Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days)
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Women, Men, Criminal justice clients

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Open Arms Inc
(301) 645-5538
2590 Business Park Court
Waldorf, MD
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification
Types of Care
Outpatient
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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