Side Effects of Lidocaine Harrodsburg KY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Alcohol Related Offenders Program
(859) 255-4682
104 West Poplar Street
Harrodsburg, KY
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Ransdell Community Mental Health Ctr
(859) 734-5486
124 East Office Street
Harrodsburg, KY
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(800) 926-8000
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Bluegrass Regional MH/MR Board Inc
(859) 253-1686
1060 Glensboro Road
Lawrenceburg, KY
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(800) 928-8000
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Bluegrass East Comprehensive Care Ctr
(859) 885-6315x232
324 Southview Drive
Nicholasville, KY
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Garrard County Comprehensive
(859) 792-2181
322 Crab Orchard Street
Lancaster, KY
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(800) 928-8000
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Bluegrass Regional MH/MR Board Inc
(859) 734-7193
212 South College Street
Harrodsburg, KY
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(800) 928-8000
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Bluegrass South Comprehensive Care Ctr
(859) 236-2726
650 High Street
Danville, KY
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(859) 928-8000
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Gaius A and R Counseling Services
(502) 839-9622
198 East Court Street
Lawrenceburg, KY
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Alcohol Related Offenders Program
(859) 885-1540
904 South Main Street
Nicholasville, KY
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Communicare Inc
(859) 336-9171
803 Bel-Vista Drive
Springfield, KY
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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