Side Effects of Lidocaine Frankfort KY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

A New Decision
(502) 227-8299
313 Saint Clair Street
Frankfort, KY
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Substance abuse
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Riverview Counseling
(502) 223-7739
214 West Main Street
Frankfort, KY
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Awareness Counseling Consulting Inc
(859) 227-5707
418 Lexington Road
Versailles, KY
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Gaius A and R Counseling Services
(502) 839-9622
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Lawrenceburg, KY
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(502) 570-9313
3107 Cincinnati Road
Georgetown, KY
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Hospital inpatient, Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days), Outpatient, Partial hospitalization/day treatment
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Bluegrass Education and
(502) 223-2017
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Frankfort, KY
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Bluegrass Regional MH/MR Board Inc
(859) 253-1686
1060 Glensboro Road
Lawrenceburg, KY
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(859) 873-7316
Comprehensive Care Ctr/Woodford City
Versailles, KY
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(502) 867-0503
121 South Hamilton Street
Georgetown, KY
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Substance abuse
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ASL or other assistance for hearing impaired, Spanish

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Thomas Peeples and Associates PSC
(502) 570-0155
1156 Lexington Road
Georgetown, KY
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Substance abuse
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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