Side Effects of Lidocaine Thomaston GA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

McIntosh Trail MH/MR/SA Comm Serv Brd
(770) 358-5252
700 Highway 341 South
Barnesville, GA
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Metro Treatment of Georgia LP
(706) 861-9390
65 White Street
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(706) 543-8338
655 Potters House Road
Jefferson, GA
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GRN CSB Lawrenceville
(770) 963-8141
175 Gwinnet Drive
Lawrenceville, GA
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Riverwoods Southern Regional
(770) 991-8500
11 Upper Riverdale Road SW
Riverdale, GA
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(706) 665-8183
159 Park Road
Talbotton, GA
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(706) 323-0174
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196 Scoggins Drive
Demorest, GA
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(800) 715-4225
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(912) 368-3502
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Hinesville, GA
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Quentin Price MD
(478) 275-6811x1175
2121 Bellevue Road
Dublin, GA
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(800) 868-5423
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(229) 928-2201
952 Anthony Drive
Americus, GA
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(800) 342-7843
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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