Side Effects of Lidocaine Strongsville OH

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Solutions Behavioral Healthcare Inc
(330) 723-9600
4274 Manhattan Circle
Brunswick, OH
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Southwest General Health Ctr/Oakview
(440) 816-8200x5756
18697 Bagley Road
Middleburg Heights, OH
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Women, Men
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Catholic Charities Services
(440) 845-7700
6753 State Road
Parma, OH
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Residential long-term treatment (more than 30 days), Outpatient
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Adolescents, Persons with co-occurring mental and substance abuse disorders
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Solutions Behavioral Healthcare Inc
(330) 723-9600
246 Northland Drive
Medina, OH
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Bridgeway Inc
(216) 281-2660
8301 Detroit Avenue
Cleveland, OH
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Substance abuse
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Women
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McIntyre Center
(440) 887-1100
6285 Pearl Road
Parma Heights, OH
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DUI/DWI offenders

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Kaiser Permanente Medical Center
(216) 265-6800
12301 Snow Road
Parma, OH
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Center for Addiction Treatment
(440) 526-3030
10000 Brecksville Road
Brecksville, OH
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Casa ALMA/Casa MARIA
(216) 459-1222
3387 Fulton Road
Cleveland, OH
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Substance abuse
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Residential long-term treatment (more than 30 days), Outpatient
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Pregnant/postpartum women, Women
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Spanish

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Recovery Resources
(216) 226-4001
14805 Detroit Avenue
Lakewood, OH
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Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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