Side Effects of Lidocaine Rockville MD

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Montgomery County Dept Health/Human
(240) 777-1680
751 Twinbrook Parkway
Rockville, MD
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Montgomery Recovery Services Inc
(301) 762-5300
14636 Rothgeb Drive
Rockville, MD
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OACES Corporation
(301) 762-1383
416 Hungerford Drive
Rockville, MD
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Avery Road Treatment Center
(301) 762-5613
14703 Avery Road
Rockville, MD
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Lawrence Court
(301) 251-8920
1 Lawrence Court
Rockville, MD
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White Flint Recovery Inc
(301) 294-6545
14636 Rothgeb Drive
Rockville, MD
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Suburban Hospital Addiction Trt Center
(301) 896-2036
6001 Montrose Road
Rockville, MD
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Potomac Ridge Behavioral Health
(301) 251-4500
14901 Broschart Road
Rockville, MD
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Avery Road Combined Care
(301) 279-8828x106
14701 Avery Road
Rockville, MD
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Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Gays and Lesbians, Women, Men, Criminal justice clients
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Journeys for Women Adult Program
(301) 294-4015
402 Hungerford Drive
Rockville, MD
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(240) 409-2158
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Substance abuse , Buprenorphine Services
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Women
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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