Side Effects of Lidocaine Paramount CA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Southern CA Alcohol and Drug Progs Inc
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8022 Somerset Street
Paramount, CA
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(310) 764-4400
404 North Rose Street
Compton, CA
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Long Beach, CA
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Los Angeles Teen Challenge
(323) 357-6993
10115 Long Beach Boulevard
Lynwood, CA
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BAART Behavioral Health Services Inc
(310) 537-5883
11315 South Atlantic Avenue
Lynwood, CA
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Southern CA Alcohol and Drug Progs Inc
(562) 461-9272
16314 Cornutta Avenue
Bellflower, CA
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Family Service of Long Beach
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16704 Clark Avenue
Bellflower, CA
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5518 North Long Beach Boulevard
Long Beach, CA
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Addiction Research and Treatment Inc
(310) 537-5883
11315 South Atlantic Avenue
Lynwood, CA
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Atlantic Recovery Services
(562) 436-3533
6500 Atlantic Avenue
Long Beach, CA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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