Side Effects of Lidocaine Oskaloosa IA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

New Directions Recovery
(641) 672-3159
1229 Avenue East
Oskaloosa, IA
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Substance abuse , Buprenorphine Services
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Women, Men, DUI/DWI offenders, Criminal justice clients

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Alcohol and Drug Dependency Servs of
(319) 524-4397
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Keokuk, IA
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Mental Health Institute
(319) 385-7231
1200 East Washington Street
Mount Pleasant, IA
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Persons with co-occurring mental and substance abuse disorders

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Community and Family Resources
(515) 832-5432
509 Division Street
Webster City, IA
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Ellsworth Municipal Hospital
(641) 648-6491
520 Talbott Street
Iowa Falls, IA
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University of IA Hospitals and Clinics
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200 Hawkins Drive
Iowa City, IA
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Clarinda, IA
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Rock Rapids, IA
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(319) 232-5363
500 East 4th Street
Waterloo, IA
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(319) 235-6571
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Substance abuse
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Mid Eastern Council on Chemical Abuse
(319) 351-4357
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Iowa City, IA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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