Side Effects of Lidocaine Nashua NH

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Youth Council
(603) 889-1090
112 West Pearl Street
Nashua, NH
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Healthy Steps Program
(603) 883-1626x7166
10 Prospect Street
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Lowell House Inc
(978) 459-8656
555 Merrimack Street
Lowell, MA
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Lowell Community Health Center Inc
(978) 937-9448
17 Warren Street
Lowell, MA
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Persons with co-occurring mental and substance abuse disorders, DUI/DWI offenders
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Metro Treatment of New Hampshire LP
(603) 622-5005
5 Driving Park Road
Manchester, NH
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Greater Nashua Council on Alcoholism
(603) 881-4848
Pine Street Extension
Nashua, NH
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Merrimack River Medical
(603) 595-3399
323 Derry Road
Hudson, NH
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Lowell House Inc
(978) 459-3371
102 Appleton Street
Lowell, MA
Hotline
(978) 459-8656
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
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Women, Men, Criminal justice clients
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Center for Family Development
(978) 459-2306
45 Merrimack Street
Lowell, MA
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Outpatient
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Habit Management
(603) 622-4747
20 Market Street
Manchester, NH
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Outpatient
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Pregnant/postpartum women, Women

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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