Side Effects of Lidocaine Moncks Corner SC

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Ernest E Kennedy Center
(843) 761-8272
306 Airport Drive
Moncks Corner, SC
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Dorchester County Commission on
(843) 871-4790
500 North Main Street
Summerville, SC
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Southwest Carolina Treatment Ctr LLC
(864) 222-9798
341 West Beltline Boulevard
Anderson, SC
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Substance abuse , Detoxification, Methadone Maintenance
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Recovery Concepts of the Carolina
(864) 306-8533
1653 East Main Street
Easley, SC
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Cornerstone
(864) 227-1001
1510 Spring Street
Greenwood, SC
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Ernest E Kennedy Center
(843) 797-7871
106 Westview Boulevard
Goose Creek, SC
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Williamsburg County Department on
(843) 355-9113x102
115 Short Street
Kingstree, SC
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(888) 852-8520
701 Grove Road
Greenville, SC
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Behavioral Health Services of
(864) 898-5800
309 East Main Street
Pickens, SC
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Union County Commission on
(864) 429-1656
201 South Herndon Street
Union, SC
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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