Side Effects of Lidocaine Minneapolis MN

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Salvation Army Harbor Light
(612) 338-0113x3112
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2616 Nicollet Avenue South
Minneapolis, MN
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Minneapolis, MN
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1025 Portland Avenue South
Minneapolis, MN
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Substance abuse
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Outpatient, Partial hospitalization/day treatment
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Persons with co-occurring mental and substance abuse disorders, Men, Criminal justice clients

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Create Inc
(612) 874-9811
1911 Pleasant Avenue South
Minneapolis, MN
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Substance abuse
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(612) 520-4004
1500 Golden Valley Road
Minneapolis, MN
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Persons with co-occurring mental and substance abuse disorders, Women, Men

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Courage Center Site
(763) 520-0329
3915 Golden Valley Road
Golden Valley, MN
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(612) 347-7600
914 South 8th Street
Minneapolis, MN
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Substance abuse , Methadone Maintenance, Buprenorphine Services
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Health Recovery Center Inc
(612) 827-7800
3255 Hennepin Avenue South
Minneapolis, MN
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Substance abuse , Detoxification, Buprenorphine Services
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Outpatient
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Pregnant/postpartum women

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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