Side Effects of Lidocaine Granite Falls NC

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Jim''s Alcohol and Drug Services
(828) 728-5851
103 Throneburg Avenue
Hudson, NC
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Hickory, NC
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Lenoir, NC
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(828) 754-5148
951 Kenham Place SW
Lenoir, NC
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Halfway house

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1146 Lenoir Rhyne Boulevard SE
Hickory, NC
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Substance abuse
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Steps to Success
(828) 291-2115
415 7th Avenue SW
Hickory, NC
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(828) 759-0070
225 Main Street NW
Lenoir, NC
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(828) 754-4900
524 Mulberry Street
Lenoir, NC
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(828) 695-6500
1985 Tate Boulevard
Hickory, NC
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(282) 320-8956
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Adolescents, Women, Criminal justice clients

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Clay Wilson and Associates
(828) 327-6026
1109 2nd Avenue SW
Hickory, NC
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Substance abuse
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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