Side Effects of Lidocaine Columbus OH

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

North Central Mental Health Services
(614) 299-6600
1301 North High Street
Columbus, OH
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Seniors/older adults
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Project Linden
(614) 294-5677
1410 Cleveland Avenue
Columbus, OH
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Substance abuse
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Outpatient
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CompDrug Corporation
(614) 224-4506
547 East 11th Avenue
Columbus, OH
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Substance abuse , Methadone Maintenance
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Pregnant/postpartum women, Women
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Traumatic Brain Injury Network
(614) 292-4559
106 McCampbell Hall
Columbus, OH
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Substance abuse
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Outpatient

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Children''s Hospital
(614) 355-8009
899 East Broad Street
Columbus, OH
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Substance abuse
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Outpatient
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Adolescents
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Fowler House
(614) 421-3155
422 East Lane Avenue
Columbus, OH
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Substance abuse
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Residential long-term treatment (more than 30 days)
Special Programs/Groups
Persons with co-occurring mental and substance abuse disorders
Language Services
ASL or other assistance for hearing impaired

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Neighborhood House Inc
(614) 252-4941
1000 Atcheson Street
Columbus, OH
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Substance abuse
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Outpatient
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Women, Men, Criminal justice clients

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Directions for Youth and Families Inc
(614) 251-0103
1414 East Broad Street
Columbus, OH
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Substance abuse
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Outpatient
Special Programs/Groups
Adolescents, Persons with co-occurring mental and substance abuse disorders, Pregnant/postpartum women, Criminal justice clients
Language Services
ASL or other assistance for hearing impaired

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Bell Center
(614) 372-3000
813 Bryden Road
Columbus, OH
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
Special Programs/Groups
Men, Criminal justice clients

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House of Hope for Alcoholics
(614) 291-4691
825 Dennison Avenue
Columbus, OH
Services Provided
Substance abuse
Types of Care
Residential long-term treatment (more than 30 days)
Special Programs/Groups
Persons with co-occurring mental and substance abuse disorders, Men
Language Services
ASL or other assistance for hearing impaired

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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