Side Effects of Lidocaine Boonton NJ

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Saint Clares Health Services
(888) 626-2111
130 Powerville Road
Boonton, NJ
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New Bridge Services Inc
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390 Main Road
Montville, NJ
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New Views Treatment Program Inc
(973) 292-4015
99 Central Avenue
Morris Plains, NJ
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Fairfield, NJ
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Bridge Inc
(973) 228-3000x20
14 Park Avenue
Caldwell, NJ
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Denville, NJ
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High Focus Centers
(973) 299-9919
1259 Route 46 East
Parsippany, NJ
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Willow Tree Center for Addiction
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Morris Plains, NJ
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Sakowitz Counseling
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63 Beaverbrook Road
Lincoln Park, NJ
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Atlantic Behavioral Health Morristown
(888) 247-1400
95 Mount Kemble Avenue
Morristown, NJ
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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