Side Effects of Lidocaine Bend OR

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Best Care Treatment Services
(541) 617-7365
461 NE Greenwood Avenue
Bend, OR
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Deschutes County Mental Health
(541) 322-7500
2577 NE Courtney Drive
Bend, OR
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So Many Road Recovery
(541) 633-7500
888 NW Hill Street
Bend, OR
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Rimrock Trails
(541) 617-4771
412 SW 8th Street
Redmond, OR
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Emergence
(541) 758-8022
425 SW Madison Avenue
Corvallis, OR
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Serenity Lane
(541) 383-0844
601 NW Harmon Boulevard
Bend, OR
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Rimrock Trails ATS
(541) 388-8459
63360 Britta Street
Bend, OR
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BestCare Treatment Services
(541) 504-2218
1514 SW Highland Avenue
Redmond, OR
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Tahana Whitecrow Foundation
(503) 585-0564
2350 Wallace Road NW
Salem, OR
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Seniors/older adults, Pregnant/postpartum women, Women, Men, DUI/DWI offenders, Criminal justice clients

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Cascadia Behavioral Healthcare
(503) 230-9654
2415 SE 43rd Avenue
Portland, OR
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Substance abuse
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Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Gays and Lesbians, DUI/DWI offenders
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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