Side Effects of Lidocaine Allegan MI

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Ottagan Addictions Recovery Inc (OAR)
(269) 686-9810
108 Chestnut Street
Allegan, MI
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(269) 372-4140x304
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Kalamazoo, MI
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(517) 887-9801
3960 Patient Care Drive
Lansing, MI
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(616) 954-1991
3351 Claystone Street SE
Grand Rapids, MI
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(269) 673-1896
217 Hubbard Street
Allegan, MI
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Psychological Consultants of MI PC
(800) 261-8850
6376 Quail Run
Kalamazoo, MI
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Saint Marys Mercy Hospital
(734) 655-5850
36475 5 Mile Road
Livonia, MI
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Catholic Charities West Michigan
(616) 796-9595x106
6660 Blair Lane
Holland, MI
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Adolescents
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(313) 576-1000x4906
4646 John Road
Detroit, MI
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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