Side Effects of Lidocaine Winfield KS

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Cowley County Community Correction
(620) 221-3454
320 East 9th Street
Winfield, KS
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Substance abuse
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Kings Alcohol/Drug Treatment Ctr LLC
(620) 221-6252
2720 East 12th Street
Winfield, KS
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Destructive Behavioral Alternatives
(620) 225-4600
106 West Frontview Street
Dodge City, KS
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1883 West 21st Street North
Wichita, KS
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South Central Kansas Foundation
(620) 672-7546
501 South Ninnescah Street
Pratt, KS
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Cowley County Mental Health and
(620) 442-4540
22214 D Street
Winfield, KS
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Arkansas City, KS
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Family Life Center
(620) 848-2300x2342
6610 SE Quakervale Road
Riverton, KS
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122 South 4th Street
Manhattan, KS
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Carousel Live LLC
(620) 241-2300
105 East Kansas Street
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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