Side Effects of Lidocaine Wetumpka AL

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

A New Direction
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c/o Elmore Community Hospital
Wetumpka, AL
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(800) 873-2887
386 Saint Lukes Drive
Montgomery, AL
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(334) 244-0702
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Lighthouse Counseling Center Inc
(334) 286-5980x222
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Montgomery, AL
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Montgomery, AL
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Bradford Health Services
(256) 760-0200
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Florence, AL
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Chemical Addictions Program Inc (CAP)
(334) 290-3800
35 Wysteria Place
Millbrook, AL
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Substance abuse
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Outpatient

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305 South Perry Street
Montgomery, AL
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Substance abuse
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Chemical Addictions Program Inc (CAP)
(334) 269-2150
1153 Air Base Boulevard
Montgomery, AL
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Adolescents
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Mountain View Hospital
(256) 546-9265x123
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Gadsden, AL
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(800) 662-1002
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Substance abuse , Detoxification, Buprenorphine Services
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Persons with co-occurring mental and substance abuse disorders, Seniors/older adults, Pregnant/postpartum women, Women, Men, DUI/DWI offenders, Criminal justice clients

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Northwest Alabama Mental Health Center
(205) 302-9000x9017
1100 7th Avenue
Jasper, AL
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(800) 489-3971
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Outpatient
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Adolescents, Persons with co-occurring mental and substance abuse disorders
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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