Side Effects of Lidocaine Pikesville MD

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

A Helping Hand LLC
(410) 653-0021
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Pikesville, MD
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Substance abuse , Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Pikesville, MD
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(410) 728-8901
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Baltimore, MD
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(410) 362-3000
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Substance abuse , Detoxification, Buprenorphine Services
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University of Maryland
(410) 542-2145
3939 Reisterstown Road
Baltimore, MD
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Substance abuse , Detoxification, Buprenorphine Services
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Women, Men, DUI/DWI offenders

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(410) 383-4996
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Baltimore, MD
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Arthur Flax''s
(410) 653-6300
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Baltimore, MD
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(410) 484-3333
17 Warren Road
Baltimore, MD
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Baltimore, MD
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5750 Park Heights Avenue
Baltimore, MD
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Substance abuse
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ASL or other assistance for hearing impaired

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(410) 367-5551x210
3643 Woodland Avenue
Baltimore, MD
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Substance abuse
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Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days)
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Persons with HIV/AIDS, Men

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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