Side Effects of Lidocaine North Adams MA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

United Counseling Service of
(802) 442-5491
Ledge Hill Road
Bennington, VT
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(802) 442-5491
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Substance abuse , Buprenorphine Services
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Outpatient
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Berkshire Medical Center/Hillcrest
(413) 442-1400x9137
165 Tor Court
Pittsfield, MA
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(413) 442-1400
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Substance abuse , Detoxification, Halfway house, Buprenorphine Services
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Persons with co-occurring mental and substance abuse disorders, Women
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Boston Public Health Commission
(617) 534-4212
723 Massachusetts Avenue
Boston, MA
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Community Healthcare Inc
(413) 746-0051x131
628 Center Street
Chicopee, MA
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Substance abuse , Methadone Maintenance
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Somerville Mental Health
(617) 623-3278
5 Hall Avenue
Somerville, MA
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Brien Center
(413) 499-0412
333 East Street
Pittsfield, MA
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Lowell House Inc
(978) 459-8656
555 Merrimack Street
Lowell, MA
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Substance abuse
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Outpatient, Partial hospitalization/day treatment
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Volunteers of America
(617) 773-0722
Long Island Campus
Boston, MA
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Substance abuse
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Eastern Middlesex Alcoholism Services
(781) 321-2600
12 Cedar Street
Malden, MA
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Victory Program/Joelyn''s Family Home
(617) 456-1201
1 Long Island Road
Boston, MA
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Substance abuse
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Residential beds for clients' children
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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