Side Effects of Lidocaine Nixa MO

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Correction Services
(417) 869-5161
2200 East Sunshine Street
Springfield, MO
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(417) 832-9707
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Springfield, MO
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Substance abuse
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Alternative Opportunities Inc
(417) 862-3455x13
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Springfield, MO
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Substance abuse , Halfway house, Buprenorphine Services
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(417) 862-3339x237
800 South Park Avenue
Springfield, MO
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Residential short-term treatment (30 days or less), Outpatient, Partial hospitalization/day treatment
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DUI/DWI offenders, Criminal justice clients

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Sigma House
(417) 862-3339x237
800 South Park Avenue
Springfield, MO
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Substance abuse , Detoxification, Halfway house
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Residential short-term treatment (30 days or less), Outpatient, Partial hospitalization/day treatment
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DUI/DWI offenders, Criminal justice clients

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Burrell Behavioral Health
(417) 269-5400
1300 Bradford Parkway
Springfield, MO
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Springfield, MO
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(417) 269-2273
1423 North Jefferson Street
Springfield, MO
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Family Guidance Ctr for Behav Hlthcare
(816) 364-1862
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(816) 468-6688
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Gladstone, MO
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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