Side Effects of Lidocaine Manchester NH

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Metro Treatment of New Hampshire LP
(603) 622-5005
5 Driving Park Road
Manchester, NH
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Habit Management
(603) 622-4747
20 Market Street
Manchester, NH
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NH Div Alcohol/Drug Abuse Prevention
(603) 668-2971
15-17 Brook Street
Manchester, NH
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
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Merrimack River Medical
(603) 595-3399
323 Derry Road
Hudson, NH
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Pregnant/postpartum women, Women, Men
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Silverman and Associates Inc
(603) 329-6440
2 Village Green Road
Hampstead, NH
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Substance abuse , Detoxification
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Gays and Lesbians, Seniors/older adults, Men

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Child and Family Services
(603) 518-4304
99 Hanover Street
Manchester, NH
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Adolescents, Persons with co-occurring mental and substance abuse disorders

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Serenity Place
(603) 625-6980
93-101 Manchester Street
Manchester, NH
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(603) 622-3020x11
235 Hanover Street
Manchester, NH
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Greater Nashua Council on Alcoholism
(603) 881-4848
Pine Street Extension
Nashua, NH
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Substance abuse , Detoxification, Halfway house
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Women, Men, Criminal justice clients

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Youth Council
(603) 889-1090
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Nashua, NH
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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