Side Effects of Lidocaine Leominster MA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

LUK Crisis Center Inc
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545 Westminster Street
Fitchburg, MA
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201 Highland Street
Clinton, MA
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171 Graham Street
Gardner, MA
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Integrated Treatment Unit
(508) 886-4746
60 Miles Road
Rutland, MA
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Residential long-term treatment (more than 30 days)
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Henry Lee Willis Community Center
(508) 755-8990
15 Northampton Street
Worcester, MA
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Spectrum Health Systems Inc
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76 Summer Street
Fitchburg, MA
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McLean Center at Fernside
(800) 906-9531
162 Mountain Road
Princeton, MA
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North Central Human Services
(978) 632-9400
31 Lake Street
Gardner, MA
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Advocates Community Counseling
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340 Maple Street
Marlborough, MA
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Spectrum Health Systems Inc
(508) 854-3320
585 Lincoln Street
Worcester, MA
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Pregnant/postpartum women, Women, Criminal justice clients
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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