Side Effects of Lidocaine Lebanon TN

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Carlton G Wood PhD and
(615) 453-0601
115 Castle Heights Avenue North
Lebanon, TN
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Cumberland Mental Health Services Inc
(615) 452-1354
1070 Old Highway 109 North
Gallatin, TN
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(800) 704-2651
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Pathfinders Inc
(615) 452-5688
432 East Main Street
Gallatin, TN
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Criminal justice clients

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Guidance Center
(615) 459-9251
131 Mayfield Drive
Smyrna, TN
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(800) 704-2651
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ASL or other assistance for hearing impaired, Spanish

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Bradford Health Services
(931) 542-9816
231 Dunbar Cave Road
Clarksville, TN
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(931) 542-9816
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Adolescents
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Pathfinders Inc
(615) 374-0709
905 Highway 231 South
Castalian Springs, TN
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Outpatient

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Cumberland Heights Outpatient
(615) 872-2757
Hermitage Business Center
Hermitage, TN
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(800) 646-9998
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Cumberland Mental Health Services Inc
(615) 824-5801
133 Indian Lake Road
Hendersonville, TN
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(800) 704-2651
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Carey Counseling Center Inc
(731) 885-8810
201 West Main Street
Union City, TN
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(800) 353-9918
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Substance abuse
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Outpatient

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Guidance Center
(615) 794-9973
1915 Columbia Avenue
Franklin, TN
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(800) 704-2651
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Outpatient
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Adolescents, DUI/DWI offenders

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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