Side Effects of Lidocaine Kent WA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Catholic Community Services
(253) 850-2527
1229 West Smith Street
Kent, WA
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Comprehensive Alcohol Services
(253) 859-5487
1609 South Central Avenue
Kent, WA
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Bi-County Co-Occurring Residential
(253) 856-1825
505 Washington Avenue South
Kent, WA
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Northwest Resources One
(206) 824-9273
22620 7th Avenue South
Des Moines, WA
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(800) 244-5767
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Alternative Counseling
(425) 251-1933
19115 West Valley Highway
Kent, WA
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Recovery Centers of King County/Kent
(253) 854-6513
505 Washington Avenue South
Kent, WA
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Kent Youth and Family Services
(253) 859-0300
232 South 2nd Avenue
Kent, WA
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Valley Cities Counseling/Consultation
(253) 939-4055
325 West Gowe Street
Kent, WA
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Adolescents, Persons with co-occurring mental and substance abuse disorders
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Armstrong Alcohol and Drug Recovery
(206) 575-1958
625 Strander Boulevard
Tukwila, WA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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