Side Effects of Lidocaine Hightstown NJ

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Personal Consulting Services
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Robbinsville, NJ
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(609) 587-7044
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Hamilton, NJ
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Family Guidance Center Corp
(609) 587-6641
946 Edgewood Avenue
Trenton, NJ
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Adolescents, Persons with HIV/AIDS
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New Horizon Treatment Services Inc
(609) 394-8988x00
132 Perry Street
Trenton, NJ
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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New Hope Foundation Inc
(732) 308-0113
2-2 Monmouth Avenue
Freehold, NJ
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Steven R Reiter
(609) 882-8051x3
2999 Princeton Pike
Lawrenceville, NJ
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(609) 924-2098
120 John Street
Princeton, NJ
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(609) 497-3300
905 Herrontown Road
Princeton, NJ
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United Progress Inc
(609) 392-2822
56 Escher Street
Trenton, NJ
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Substance abuse , Halfway house
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Outpatient

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(609) 394-8000
1418 South Broad Street
Trenton, NJ
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Substance abuse
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Outpatient, Partial hospitalization/day treatment
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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