Side Effects of Lidocaine Grosse Pointe MI

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Catholic Social Services of
(313) 821-2590
15200 East Jefferson Avenue
Grosse Pointe Park, MI
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Substance abuse
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Outpatient
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Seniors/older adults, Criminal justice clients
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ASL or other assistance for hearing impaired

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Family Service Inc
(313) 821-0469
14200 Kerchval
Detroit, MI
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Adolescents, DUI/DWI offenders
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Downriver Mental Health Clinic
(586) 777-9000
24715 Littlemack Street
Saint Clair Shores, MI
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Substance abuse
Types of Care
Outpatient
Language Services
Italian

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Eastwood Clinics
(586) 445-2210
20811 Kelly Road
Eastpointe, MI
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, DUI/DWI offenders
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A Few Steps
(313) 521-7877
14219 Flanders Street
Detroit, MI
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Substance abuse
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Outpatient
Special Programs/Groups
Adolescents, Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, DUI/DWI offenders, Criminal justice clients

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Positive Images
(313) 822-6940x117
13336-40 East Warren
Detroit, MI
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Persons with HIV/AIDS, Pregnant/postpartum women, Women, Criminal justice clients

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Northeast Guidance Center
(313) 824-8000
12800 East Warren Avenue
Detroit, MI
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Men

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Jefferson House
(313) 331-8900
8311 East Jefferson Avenue
Detroit, MI
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Substance abuse
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Residential long-term treatment (more than 30 days)
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Men

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Heartline Inc
(313) 923-4200
8201 Sylvester Street
Detroit, MI
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Substance abuse , Halfway house
Types of Care
Residential long-term treatment (more than 30 days)

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Operation Get Down Inc
(313) 921-9422
10100 Harper Street
Detroit, MI
Services Provided
Substance abuse , Halfway house
Types of Care
Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days), Outpatient
Special Programs/Groups
Persons with co-occurring mental and substance abuse disorders, Women, Residential beds for clients' children, Men, Criminal justice clients

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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