Side Effects of Lidocaine Gibsonia PA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Arche Wellness LLC
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(412) 963-7077
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Pittsburgh, PA
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(724) 776-4844
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(724) 226-0664x833
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Tarentum, PA
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Progressive Medical Specialists Inc
(412) 391-6384
2900 Smallman Street
Pittsburgh, PA
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Substance abuse , Methadone Maintenance, Methadone Detoxification
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Mercy Behavioral Health
(724) 933-8200
9983 Perry Highway
Wexford, PA
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(724) 265-4100
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Rural Ridge, PA
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Discovery House
(724) 779-2010
301 Smith Drive
Cranberry Township, PA
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Substance abuse , Methadone Maintenance
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(724) 226-0664
321 East Fifth Avenue
Tarentum, PA
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(888) 222-4200
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Women, Men, Criminal justice clients

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(412) 255-8717x204
59 31st Street
Pittsburgh, PA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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