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Side Effects of Lidocaine Franklinton LA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Washington Parish
(985) 732-6655
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Bogalusa, LA
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New Horizon Youth Service B/Hammond
(985) 345-1171
47257 River Road
Hammond, LA
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Bastrop Addictive Disorders Clinic
(318) 283-0868
320 South Franklin Street
Bastrop, LA
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Alternative Outpatient Services
(337) 234-0830
128 Demanade Boulevard
Lafayette, LA
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Thibodaux Addictive Disorders Clinic
(985) 447-0851
303 Hickory Street
Thibodaux, LA
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Stages of Recovery
(337) 430-0444
1510 Hodges Street
Lake Charles, LA
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Central City Behavioral Health Center
(504) 568-6650
2221 Phillip Street
New Orleans, LA
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Slidell, LA
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Saint Charles Parish Hospital
(985) 785-6242
1057 Paul Maillard Road
Luling, LA
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Substance abuse , Detoxification
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Persons with co-occurring mental and substance abuse disorders
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DeRidder ADC
(337) 463-7310
417 North Pine Street
DeRidder, LA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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