Side Effects of Lidocaine Fostoria OH

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Fostoria Alcohol/Drug Center
(419) 435-9465
222 South Main Street
Fostoria, OH
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Family Resource Centers
(419) 422-8616
1941 Carlin Street
Findlay, OH
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Lutheran Social Services
(419) 334-3431
512 East State Street
Fremont, OH
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(800) 567-4673
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Substance abuse
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Outpatient
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Adolescents, Criminal justice clients

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Behavioral Connections of Wood County
(419) 352-5387
320 West Gypsy Lane Road
Bowling Green, OH
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(800) 472-9411
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Substance abuse
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Outpatient
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Women, Men, Criminal justice clients
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Consolidated Care Inc
(937) 599-1975
118 Maple Street
Bellefontaine, OH
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Firelands Counseling/Recovery Services
(419) 448-9440
76 Ashwood Road
Tiffin, OH
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(800) 826-1306
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Century Health South Campus
(419) 425-5050
1918 North Main Street
Findlay, OH
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(888) 936-7116
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Substance abuse
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Firelands Counseling/Recovery Services
(419) 332-5524
675 Bartson Road
Fremont, OH
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(800) 826-1306
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Substance abuse
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Bridgeway Inc
(216) 281-2660
8301 Detroit Avenue
Cleveland, OH
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(216) 281-2660
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Substance abuse
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Outpatient
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Women
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Dayton VA Medical Center
(937) 268-6511x1314
4100 West 3rd Street
Dayton, OH
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Substance abuse , Detoxification, Methadone Maintenance, Methadone Detoxification
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Outpatient
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Persons with co-occurring mental and substance abuse disorders, Pregnant/postpartum women, Women, Men
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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