Side Effects of Lidocaine Enumclaw WA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Rainier Counseling
(360) 802-0446
847 Blake Street
Enumclaw, WA
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Exodus Counseling and Treatment Servs
(253) 891-2662
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Sumner, WA
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Valley Cities Counseling/Consultation
(253) 939-4055
2704 I Street
Auburn, WA
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All About Choices Inc
(253) 218-0317
1833 Auburn Way North
Auburn, WA
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Assessment/Treatment Associates Inc
(253) 205-8200
4508 Auburn Way North
Auburn, WA
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Prosperity Counseling and
(253) 863-9667
1723 Bonney Avenue
Sumner, WA
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Center East
(253) 863-0682
1110 Fryar Avenue
Sumner, WA
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Future Visions Program Inc
(253) 735-2718
620 M Street NE
Auburn, WA
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Lakeside Milam Recovery Centers Inc
(253) 859-6436
721 45th Street NE
Auburn, WA
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Alcohol Drug Services of WA
(253) 939-2243
4204 Aubrun Way North
Auburn, WA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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