Side Effects of Lidocaine Elizabeth NJ

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Herbert Goodfriend LCSW LCADC
(908) 351-6080
230 West Jersey Street
Elizabeth, NJ
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Bridgeway Inc
(908) 355-7200
567 Morris Avenue
Elizabeth, NJ
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Intervention Specialist LLC
(908) 289-0700
453 Morris Avenue
Elizabeth, NJ
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Adolescents, Persons with co-occurring mental and substance abuse disorders, Men, DUI/DWI offenders, Criminal justice clients
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Lynn Laucik
(908) 851-2223
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Union, NJ
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Camelot of Staten Island Inc
(718) 981-8117
Louis Harris
Staten Island, NY
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Proceed Inc
(908) 351-7727
1126 Dickinson Street
Elizabeth, NJ
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Trinitas Hospital
(908) 994-7090
654 East Jersey Street
Elizabeth, NJ
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Daytop Village Inc
(718) 981-3136
1915 Forest Avenue
Staten Island, NY
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New Hope Behavioral Health Center
(973) 373-5100
277-285 Coit Street
Irvington, NJ
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Substance abuse
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Outpatient, Partial hospitalization/day treatment
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Persons with co-occurring mental and substance abuse disorders, Women, Men
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American Habitare
(973) 799-0508
687 Frelinghuysen Avenue
Newark, NJ
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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