Side Effects of Lidocaine Comstock Park MI

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Arbor Circle Corporation
(616) 459-7215
1115 Ball Avenue
Grand Rapids, MI
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North Kent Guidance Services LLC
(616) 361-5001
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Grand Rapids, MI
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Pine Rest Christian Mental Hlth Servs
(616) 222-3720
550 3 Mile Road
Grand Rapids, MI
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Catholic Charities West Michigan
(616) 356-6289
40 Jefferson Street SE
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Pine Rest Christian Mental Hlth Servs
(616) 455-5270
300 68th Street SE
Grand Rapids, MI
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West Michigan Addiction Consultants PC
(616) 365-8800
3001 Fuller Avenue NE
Grand Rapids, MI
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Pine Rest Christian Mental Hlth Servs
(616) 364-1500
1700 East Beltline Street
Grand Rapids, MI
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SOS Counseling Services
(616) 732-8110
942 West Fulton Street
Grand Rapids, MI
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Our Hope Association
(616) 451-2039
324 Lyon Street NE
Grand Rapids, MI
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Substance abuse
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Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days), Outpatient
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Persons with co-occurring mental and substance abuse disorders, Women, Criminal justice clients
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Ottawa, Romanian, Spanish

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Pine Rest
(616) 227-6861
523 Lyon Street NE
Grand Rapids, MI
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Substance abuse , Buprenorphine Services
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Men
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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