Side Effects of Lidocaine Clinton NC

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Green Freida
(910) 592-4507
307-A Vance Street
Clinton, NC
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Substance abuse , Detoxification
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Karl H Stanley
(919) 418-0388
207 West Main Street
Clinton, NC
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Substance abuse
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(704) 334-4635
907 West 1st Street
Charlotte, NC
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
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(910) 251-8930
1314 South 16th Street
Wilmington, NC
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(704) 484-2450
616 East Marion Street
Shelby, NC
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders

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McCoy and Associates
(910) 592-2818
409 Cooper Drive
Clinton, NC
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Substance abuse
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Outpatient
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DUI/DWI offenders

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(919) 573-6520
4112 Blue Ridge Road
Raleigh, NC
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(252) 519-2273
1704 Highway 158
Roanoke Rapids, NC
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Substance abuse
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Outpatient
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(828) 659-3966
117 West Medical Court
Marion, NC
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Substance abuse , Methadone Maintenance
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Southeast Addictions Institute and
(704) 561-0920
5601 Executive Center Drive
Charlotte, NC
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Substance abuse
Types of Care
Outpatient
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Persons with co-occurring mental and substance abuse disorders, DUI/DWI offenders
Language Services
Spanish

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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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