Side Effects of Lidocaine Chalfont PA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Childrens Aid Society
(215) 362-8422
2506 N Broad Street
Colmar, PA
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Community Service Foundation Inc
(215) 348-8881
801 West 2nd Street
Lansdale, PA
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Partial hospitalization/day treatment

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350 South Main Street
Doylestown, PA
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Substance abuse
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Lansdale, PA
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UHS Keystone Center
(215) 542-4825
722 East Butler Pike
Ambler, PA
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Substance abuse
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Outpatient, Partial hospitalization/day treatment
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Project Transition
(215) 491-0166
1700 Street Road
Warrington, PA
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Substance abuse
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Residential long-term treatment (more than 30 days), Outpatient, Partial hospitalization/day treatment
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Persons with co-occurring mental and substance abuse disorders

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Aldie Counseling Center
(215) 345-8530x110
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Doylestown, PA
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Rehab After Work
(215) 348-1720
Route 202 and Mechanicsville Road
Doylestown, PA
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Substance abuse
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Outpatient
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Family Service Assoc of Bucks County
(215) 345-0550
708 North Shady Retreat Road
Doylestown, PA
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Substance abuse
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Outpatient
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Persons with co-occurring mental and substance abuse disorders
Language Services
Russian, Spanish

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Horsham Clinic
(215) 643-7800
722 East Butler Pike
Ambler, PA
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Substance abuse , Detoxification
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Hospital inpatient
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Persons with co-occurring mental and substance abuse disorders
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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