Side Effects of Lidocaine Arlington WA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Stillaguamish Tribe of Indians
(360) 653-1104
4126 172nd Street NE
Arlington, WA
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Island Crossing Counseling Services
(360) 652-9640x19
21123 Smokey Point Boulevard
Arlington, WA
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Catholic Community Services
(360) 651-2366
1227 2nd Street
Marysville, WA
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North Sound Assessment and
(425) 252-1779
1316 Wall Street
Everett, WA
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Port Gardner Bay Recovery
(425) 252-4656
2722 Colby Avenue
Everett, WA
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Alpine Recovery Services Inc
(360) 658-1388
16404 Smokey Point Boulevard
Arlington, WA
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Tulalip Tribal Family Services
(360) 651-3351
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Marysville, WA
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Clearview Counseling
(360) 653-0374x111
1106 Columbia Avenue
Marysville, WA
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Evergreen Manor Inc
(425) 259-5842
2932 Hoyt Avenue
Everett, WA
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Persons with co-occurring mental and substance abuse disorders, Pregnant/postpartum women, Women, Criminal justice clients
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Catholic Community Services
(425) 258-5270
2610 Wetmore Avenue
Everett, WA
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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