Side Effects of Lidocaine Ames IA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Community and Family Resources
(515) 232-3206
1619 South High Avenue
Ames, IA
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(515) 233-3141
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Ames, IA
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110 North Park Place
Cresco, IA
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Persons with co-occurring mental and substance abuse disorders, DUI/DWI offenders

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Jackson Recovery Centers Inc
(712) 546-7868
19 Lincoln Street SE
Le Mars, IA
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Davenport, IA
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Seven 12 House
(515) 233-5048
712 Burnett Street
Ames, IA
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Boone, IA
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800 5th Street
Sioux City, IA
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Manning Regional Healthcare Center
(712) 655-2300x350
410 Main Street
Manning, IA
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(800) 656-6372
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Hospital inpatient, Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days), Outpatient, Partial hospitalization/day treatment
Special Programs/Groups
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Zion Recovery Services
(712) 542-3720
1800 North 16
Clarinda, IA
Hotline
(641) 337-5385
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Residential short-term treatment (30 days or less), Residential long-term treatment (more than 30 days)
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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