Side Effects of Lidocaine Agawam MA

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Baystate Medical Center
(413) 739-4732
59 Saint James Avenue
Springfield, MA
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Substance abuse
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Habit OPCO
(413) 733-3488
2257 Main Street
Springfield, MA
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Substance abuse , Methadone Maintenance, Methadone Detoxification, Buprenorphine Services
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Child and Family Services of
(413) 737-1426x114
367 Pine Street
Springfield, MA
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Adolescents, Persons with co-occurring mental and substance abuse disorders
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Gandara Center Inc
(413) 781-2234x104
33 Arch Street
Springfield, MA
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Substance abuse , Halfway house
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Residential long-term treatment (more than 30 days)
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Persons with HIV/AIDS, Men
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Gandara Center Inc
(413) 736-0395
2155 Main Street
Springfield, MA
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Substance abuse
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Outpatient
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Adolescents, DUI/DWI offenders
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Phoenix Houses of New England
(413) 733-2178
5 Madison Avenue
Springfield, MA
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Substance abuse
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Persons with co-occurring mental and substance abuse disorders, Women, Men

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Baystate Medical Center
(413) 794-8409
140 High Street
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Phoenix House OP Services of Western
(413) 739-2440
15 Mulberry Street
Springfield, MA
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Substance abuse , Buprenorphine Services
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Adolescents, Criminal justice clients
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Baystate Medical Center
(413) 733-7891
89 Belmont Avenue
Springfield, MA
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Substance abuse
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Residential long-term treatment (more than 30 days)
Special Programs/Groups
Pregnant/postpartum women, Women, Residential beds for clients' children

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Northern Educational Services Inc
(413) 787-2101x124
736 State Street
Springfield, MA
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(800) 925-0127
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Substance abuse
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Outpatient
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Side Effects of Lidocaine

INTRODUCTION TO LIDOCAINE

Lidocaine is a substance administered intravenous in the treatment of ventricular arrhythmias, is generally very well tolerated. The major side effects primarily involve the central nervous system, the cardiovascular system, and the gastrointestinal tract.

LIDOCAINE NEUROLOGIC TOXICITY

The most common adverse effect of lidocaine is central nervous system (CNS) toxicity. The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of the drug. These side effects may be particularly frequent in the elderly or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful bedside sign of toxicity. Other neurologic side effects include insomnia or drowsiness, lightheadedness, dysarthria and slurred speech, ataxia, depression, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized. This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

LIDOCAINE CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of lidocaine therapy which is general...

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